We measured the concentration of OPG and TGFb-1 in the suprarenal segments of angiotensin II treated mice that developed AAA (mean maximum diameter 2.67 ± 0.24, n = 9) and those that did not (mean maximum diameter 1.26 ± 0.25, n = 9, p < 0.01) and found that both proteins were expressed at higher concentrations in aortas of mice with aneurysms, p < 0.05 (Figure 2A). This evidence concerns the gene TNFRSF11B and triple-A syndrome.