The more common genetic abnormalities found in PTC are the radio-induced RET/PTC rearrangements and the mutations of BRAF and RAS genes, while PAX8/PPARγ fusion gene and the loss of heterozigosity (LOH) on 3p and 7q loci as well as RAS mutations are frequently encountered in FTC. The gene discussed is PAX8; the disease is thyroid cancer, nonmedullary, 2.