MET and thyroid cancer, nonmedullary, 2: We have demonstrated that the whole morphogenetic pathway HGF/c-met/STAT3 is over-expressed in PTC (Fig. 1C), and is highly specific for this type of thyroid malignancy (100% of PTC tested; none of the FTC or ATC), suggesting that such autocrine signalling pathway may be relevant for the establishment of the papillary phenotype (Trovato et al. 2003).