Another good example of how a meticulous echocardiographic examination can detect the presence of a specific and unusual cause for severe ventricular hypertrophy, is Fabry's disease – an X-linked metabolic storage disease where glycosphingolipid accumulates in the myocardium and other tissues, due to deficient activity of the enzyme alpha-galactosidase A [17]. Here, GLA is linked to Ventricular hypertrophy.