In a recent study with 97 Brazilian patients with pancreatic ductal adenocarcinoma, pancreatic neuroendocrine tumors and chronic pancreatitis, a K-ras mutation at codon 12 was found notably present in malignancies but absent in chronic pancreatitis and pancreatic neuroendocrine tumors [30]. Here, KRAS is linked to pancreatic neuroendocrine tumor.