AVP and alkaline phosphatase measurement: Other reported changes are: changes in body fluid compartments, with inappropriate low secretion of anti-diuretic hormone (ADH), reduced plasma volume, elevated basal metabolic rate by about 2%, weight loss and negative energy balance and lowered fasting blood glucose level (possibly due to its lower absorption) than at sea level.[16] All these possible changes might justify the inappropriateness of Ranson's criteria in the prediction of severity of AP in our situation.