MAPK3 and ulnar-mammary syndrome: UMs displaying activated ERK1/2 as well as phosphorylated HSP27 were most common, whereas signals for phosphorylated ERK1/2 were low in metastasis tissue (MET1-3) and metastatic UM cell lines (OMM1, OMM2.3 and OMM2.5) (Figure 1).