TGFB1 and lung cancer: While a Korean study showed that the variant T genotypes of the TGFB1 -509C>T SNP were associated with a reduced risk of lung cancer [33], a Chinese study of 414 patients and 414 controls [34] reported that the genotypes were not associated with an overall risk of developing gastric cancer but with a decreased risk of risk of stage I or II gastric cancer.