The median overall survival (OS) for patients with NSCLC who had low levels of CXCR4 expression on MNC (≤ 2500 CXCR4 positive cells/ml) was not reached versus a median OS of 14 weeks for those with a CXCR4 expression level > 2500 CXCR4 positive cells/ml (Figure 4). Here, CXCR4 is linked to non-small cell lung carcinoma.