Taguchi et al, analysing head and neck squamous cell carcinomas did not observe any significant differences at EGFR mRNA and protein levels in cell lines harbouring different genotypes, despite the described higher sensitivity of (G/A) heterozygous when compared with (G/G) homozygous cell lines to Gefitinib [32]. This evidence concerns the gene EGFR and head and neck squamous cell carcinoma.