Some studies have shown that genetic polymorphisms of the XRCC1 gene are associated with response to platinum-based chemotherapy in non-small-cell lung cancer, colorectal cancer, and breast cancer [8,9], but few studies have investigated the association of XRCC1 SNPs with response to chemotherapy in locally advanced cervical carcinoma. The gene discussed is XRCC1; the disease is non-small cell lung carcinoma.