In PLA2G4A, a mutation was detected in the UPF1 siRNA-transfected GP202 gastric cancer cells, at position 1012 (mRNA seq NM_024420.1) resulting in a C to T substitution at position 303 of the protein, but this mutation did not result in a different amino acid (GAC to GAT (Aspartate)). Here, UPF1 is linked to gastric cancer.