In the experiments with the DMN model of liver fibrosis, Cordyceps and Gynostemma Pentaphyllammak had strong effects on reducing hepatic hydroxyproline contents and attenuating collagen deposition, while Radix Salvia Miltiorrhizae and Cordyceps Extract piece had significant effects on improving liver function such as reducing serum ALT activity. The gene discussed is GPT; the disease is Hepatic fibrosis.