HBG2 and hemorrhage: In the subsequent early subacute phase (> 3 days after onset of hemorrhage), the transformation of intracellular deoxyhemoglobin to methemoglobin is known to induce a change of the MR-signal to high intensities on T1WI and low intensities on T2WI images, whereas in the late subacute phase (> 7 days post hemorrhage), the occurrence of extracellular methemoglobin results in high signals in both T1WI and T2WI, which contrasts much better with the native tumor and liver parenchymal signal.