Our aim was to find whether there is any association of the CHOP 5'UTR-c.279T>C and +nt30C>T genotypes and corresponding haplotypes (the latter contributing to T2D) [7] with body mass index (BMI) ≥ 25 (hereby defined as overweight condition/pre-obesity) and/or with tumors/cancer in an Italian dataset. Here, DDIT3 is linked to cancer.