MC2R and Aarskog-Scott syndrome, X-linked: Studies of the expression of the MRAP gene in humans reveal a wider pattern of expression than that of the MC2R.7 This suggests that MRAP may have additional roles to those related to the MC2R, and we have demonstrated an interaction with each of the melanocortin receptors.12 Therefore, examination of any discrepancies between FGD types 1 and 2 may provide important clues to other functions of MRAP.