SOCS1 and Crohn disease: Two emerge with highly significant GRAIL scores: rs8178556 on chromosome 21 (IFNAR1, ptext = 1.7×10−4) and rs12928822 on chromosome 16 (SOCS1, ptext = 8.2×10−4) suggesting these independent regions may lead to novel associated SNPs for Crohn's disease (see Table S7).