PRSS8 and carcinoma: Among the carcinomas in this study 23 carcinomas were designated as Dukes'stage A, 47 carcinomas as stage B, 39 carcinomas as stage C and none of the samples were classified as stage D. No tendency and no significant difference (one-way ANOVA and Tukey's post test for paired comparison) were seen when comparing the prostasin and PN-1 mRNA levels with the designated Dukes'stages.