Of the 95 MDR-1 Pgp positive RCC, 6% (6/95) scored 1, 18% (17/95) scored 2, 45% (43/95) scored 3 and 31% (29/95) scored 4 percentage staining of MDR-1 Pg-p. The gene discussed is ABCB1; the disease is renal cell carcinoma.