To date, a large number of iPSC lines from various diseases such as amyotrophic lateral sclerosis [195]; Parkinson's disease [196]; type I diabetes [197]; spinal muscular atrophy [198]; adenosine deaminase deficiency-related severe combined immunodeficiency (ADA-SCID); Shwachman-Bodian-Diamond syndrome; Gaucher disease; and type III, Duchenne, and Becker muscular dystrophy [199] have been reported. Here, ADA is linked to severe combined immunodeficiency.