IGFBP3 and renal cell carcinoma: For RCC risk, the final model (overall χ2 = 11.9336 P = 0.0026) retained only MMP1 and MMP3 (P = 0.0291 and 0.0006731) and excluded SNPs in CDH1, IGFBP3, STK15 and VEGF as significant variables.