The genes SRGAP2P1 (SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1), TMED2 (transmembrane emp24 domain trafficking protein 2) and FAM62B (family with sequence similarity 62 (C2 domain containing) member B) shared similar upregulation in both ALL and AML with MLL translocation but their role in leukemogenesis remains to be explored. The gene discussed is ESYT2; the disease is acute lymphoblastic leukemia.