COMT and schizophrenia: Our meta-analyses of the SchizophreniaGene online database revealed that among the four genetic variants investigated in our study, only the 5-HT2AR A-1438 G polymorphism is likely associated with the risk for schizophrenia (5-HT2AR A-1438 G: odds ratio in Caucasians [OR] = 1.17; COMT Val158Met: OR = 1.01; NRG-1 Arg38Gln: OR = .97; http://www.schizophreniaforum.org) (18).