ESR1 and breast carcinoma: In the current analysis, the most significant SNPs identified in this dataset were rs2107425 on chr 11p15.5 (P = 0.0012) and rs3817198 in LSP1 (P = 0.0016), both of which have been identified as susceptibility alleles for breast cancer, and rs9322336, which is located in the oestrogen receptor (ESR1) gene (P = 0.0013).