We also confirmed PAR1 expression in samples from our patients using immunofluorescent staining for PAR1 present in the surface of the cells (Figure 1c), and found 30 patients out of 50 high grade breast cancer patients included in this study (70%) express PAR1; highly significant when compared with the rest of the group (P = 0.0001). Here, F2R is linked to breast carcinoma.