TGFBR1 and malignant colon neoplasm: Recent studies suggest that the association of the TGFBR1*6A allele with colon cancer is either weak (OR: 1.2; 95% CI: 1.01–1.43) [7] or of borderline significance (OR: 1.13; 95% CI: 0.98–1.30) [10].