To date, several missense mutations in LRRK2 have been linked to autosomal dominantly inherited PD (e.g. R1441C/G, Y1699C, G2019S, I2020T), and many additional LRRK2 variants are being evaluated for conclusive pathogenicity or increased risk for PD [23]. The gene discussed is LRRK2; the disease is Parkinson disease.