Although there were only two FHC samples, this condition has a distinct clinical phenotype from other types of uveitis, and several previous studies have identified differences between FHC and CU patients in vitreous cellular infiltrate and cytokine production, suggesting a Th1 mediated response with CD8+ cells and few B cells as characteristic of FHC [27,28]. This evidence concerns the gene CD8A and hypercholesterolemia, familial, 1.