Various studies in colorectal cancer (Park et al, 2003; Stoehlmacher et al, 2004; Viguier et al, 2005; Ruzzo et al, 2007) and lung cancer patients (Su et al, 2007) suggest that the ERCC1 118CC genotype is associated with longer OS and a better response towards platinum agents. This evidence concerns the gene ERCC1 and lung cancer.