After 30 days tumours transfected with pCMV-dBP4 were significantly smaller (10.45±0.76 mm) than tumours transfected with pCMV-BP4 (15.26±0.87 mm), or pCMV (15.55±2.29 mm) (Figure 3C). The gene discussed is IGFBP4; the disease is neoplasm.