The frequency of this rare allele in our patients was spread unequally; it was absent in the patients with LPL deficiency but was more common in the patients with HPND than in the controls with hypertriglyceridaemia, and may perhaps have contributed to a greater predisposition in the former for the development of pancreatitis due to the chylomicrons. Here, LPL is linked to hypertriglyceridemia.