Third, the APD does not capture data on additional factors that may have relevance and, therefore we are unable to comment on whether these modified the risk of early hypoglycemia or BG variability (i.e. early nutritional support, dextrose administration, oral hypoglycemic medications, insulin therapy, or concomitant corticosteroid therapy) and on how, if at all, the hypoglycemia was treated. The gene discussed is INS; the disease is Hypoglycemia.