Thus, Billeskov et al. demonstrated that TB10.4 3–11 specific CD8 T cells comprised a large part of the CD8 T cell population in the lungs of infected C57BL/6 mice at 50 weeks post infection [3] and Kamath et al. showed that at 32 weeks post infection there was approximately 16% TB10.4 20–28 specific CD8 T cells in the lungs of infected BALB/c mice [5]. This evidence concerns the gene CD8A and infection.