LAMP1 and infection: Our results also indicate that whereas the function of CD4/10.4 and CD8/10.4 cells may be partially overlapping in the early stages of infection (judged by the small differences in polyfunctionality, CD107a/b expression, and in vivo cytoxicity), at later time points these cells showed significant differences in these markers suggesting more disparate effector functions of the subsets in the late stages of infection.