In malignant tumor, the level of general demethylation and the frequency of demethylation increase with tumor progression [31], [32], and demethylation of individual CpG dinucleotides located in C-MYC, Ha RAS, and ERB-A1 proto-oncogene was revealed in human tumors [33]–[36]. The gene discussed is MYC; the disease is neoplasm.