ANXA2 and familial pancreatic carcinoma: Upregulation of ANX2 expression has been reported in hepatocellular carcinoma (Frohlich et al, 1990), lung cancer (Cole et al, 1992), pancreatic cancer (Diaz et al, 2004; Esposito et al, 2006), breast cancer (Sharma et al, 2006), gastrointestinal cancer (Singh, 2007), glioma (Reeves et al, 1992) and colorectal cancer (Emoto et al, 2001b).