The extent of CXCR4 overexpression correlated with bone metastases (correlation coefficient: 0.551; P < 0.001), margin status (correlation coefficient: 0.206;P = 0.005), and hilar lymph node metastases (correlation coefficient: 0.198; P = 0.008). The gene discussed is CXCR4; the disease is metastatic malignant neoplasm in the lymph nodes.