In addition, the increased FGFR2 gene expression has been related to the genetic variants in intron 2 of the FGFR2 gene [17] and deregulation of FGFR2 gene expression and/or gene mutation has been identified in various kinds of human cancers, such as breast, prostate, endometrial, colon, bladder, and thyroid cancers [17-22]. The gene discussed is FGFR2; the disease is cancer.