IFNG and neoplasm: Furthermore, IFN-γ induces enhanced expression of key immune regulatory molecules such as class I and class II major histocompatibility complex (MHC) molecules and intercellular adhesion molecule-1 (ICAM-1) on the surface of tumor cells, which may lead to improved antigen presentation to dendritic cells as well as to pre-existing primed CTLs for further expansion and enhanced destruction of tumor cells [2,3].