The relative importance of plasminogen in infectious disease is indicated by the surface-associated plasminogen-binding properties manifested by diverse species of human pathogens, including Yersina pestis, Listeria monocytogenes, several species of Streptococcus, and four pathogenic fungal species, C. albicans, Aspergillus fumigatus, Paracoccidioides brasiliensis, and Pneumocystis jiroveci (carinii)[27], [41], [43]–[48]. The gene discussed is PLG; the disease is infectious disease.