The UHRF1 was significantly overexpressed in bladder tumours (P<0.0001, Mann–Whitney's U-test, Figure 1), especially in 12 upper tract TCCs (P<0.0001, Kruskal–Wallis test, Figure 1): 10 percentile of the upper tract TCCs is higher than 50 percentile of the bladder-origin bladder cancers. The gene discussed is UHRF1; the disease is urinary bladder neoplasm.