Such AVP effect is mediated by AVPR1B [1] and ACTH measurements in mice have indicated that AVP plays important roles in response to some acute stressors (e.g. hypoglycemia, forced swim stress, lipopolysaccharyde challenge and ethanol intoxication, change in environment), as well as in times of chronic stress [2,79-83]. The gene discussed is AVP; the disease is Hypoglycemia.