In people with diabetes, the plasma PAI-1 levels were positively correlated with serum total cholesterol levels (r = 0.41, p = 0.001), LDL cholesterol (r = 0.266, p = 0.045), triglyceride (r = 0.35, p = 0.006), and with HbA1c(r = 0.38, p = 0.003). This evidence concerns the gene SERPINE1 and diabetes mellitus.