HDAC7 and Huntington disease: As HDAC inhibitors have been shown to ameliorate the dysregulation of gene expression in HD models systems [28], [29], [43], we used RT-qPCR to measure the level of expression of a set of genes of interest in the striatum and cerebellum of WT, R6/2, Hdac7+/− and R6/2-Hdac7+/− mice aged 15 weeks.