CRP binds with high avidity to monocytes and neutrophils from R131 homozygotes, but shows strongly decreased binding to cells from FcγRIIa H131 homozygotes and intermediate binding to FcγRIIa heterozygotes, implying that the HH131 genotype may thus be less susceptible to coronary heart disease (CHD) [24]. This evidence concerns the gene CRP and coronary artery disorder.