Similarly, although further study is necessary to confirm the qualitative interaction between smoking and genotype in relation to lung cancer susceptibility for the CYP1A1 rs2606345, this finding is particularly interesting, considering that this SNP is not included in the HapMap database or in the common platforms used for GWAS, although it is in relatively strong LD with other SNPs in these platforms. The gene discussed is CYP1A1; the disease is lung cancer.