Our present data, consistent with those of other authors [8,11,14,22,25] showed that adiponectin levels was negatively correlated with triglycerides in patients and with BMI only in the control subjects, but in contrast to the others we found negative correlation with total cholesterol in patients and any correlation with other CAD risk factors such as smoking[14], age, DM, HTN, HDL and LDL. The gene discussed is ADIPOQ; the disease is diabetes mellitus.