Idd14 covers 36,000,000 bp and 385 genes on chromosome 13, among which six candidates are mapped: prl, CD83, Bmp6, Irf4, Syk, and cdkal1. Prolactin PRL enhanced a Th2 response, which may reflect the preventive effect of PRL against development of multiple low-dose STZ diabetes in mice [124, 125]. This evidence concerns the gene PRL and diabetes mellitus.