THBS3 and neoplasm: The genes were chosen because they may define MHC haplotypes or because of their relevance to tumor biology; i.e., DLA-88 is an MHC class I gene [20], homologues of TSP-3 are known to regulate angiogenesis [21], and the SWI/SNF related gene SMARCA-1 is an ATP dependent chromatin remodeler important for the regulation of transcription, DNA replication, and DNA repair that is abnormally expressed in certain tumors [22].