IDO1 and myeloid sarcoma: Consistent with a critical role for thesespecific glucocorticoid-target genes in providing relief against MS, ectopicstudies have revealed that small increases in gene expression of the enzymesHMOX-1 [9], IDO [52, 54], or the mitochondrial superoxide dismutase (SOD2;[86]) prevent or reverse autoimmune demyelination.