Of these, mutations in 9 crystallin genes have been associated with autosomal dominant cataracts (CRYAA, CRYAB, CRYBB1, CRYBB2, CRYBA1/A3, CRYBA4, CRYGC, CRYGD, and CRYGS) but only 3 with autosomal recessive cataracts (CRYAA, CRYBB1, and CRYBB3). The gene discussed is CRYAA; the disease is Autosomal dominant optic atrophy and cataract.