Stat5a is not insertionally mutated in the murine tumors but it is a validated leukemia gene and functions in the same signaling pathway as IL2RG. Most of the genes that clustered with the LMO2-high class were also highly expressed in the mouse tumors and some showed differential expression in comparison to normal thymus or tumor 7065 (Figure 5B). This evidence concerns the gene IL2RG and neoplasm.